Gen 3:15 And I will put enmity between thee and the woman, and between thy seed and her seed; it shall bruise thy head, and thou shalt bruise his heel.
It is Advent, when people all over the world anticipate the day we remember Jesus' birth. No one knows exactly which day He was born, and probably it was not in mid winter. But the day of His birth is not as important as the fact of His birth and the reason He was born. God knew from the beginning that a remedy for man's imperfection would be needed, and He planned for that remedy to be provided at what He knew would be the right time and the right place.
Genesis 3:15 is generally accepted as being the first prophecy in Scripture about the Messiah, the Christ, the Anointed One. It says that He would be born of a woman, so He would be human. But He would be "her seed." This is an odd phrase because the seed is what is planted, and in the Bible refers to men, not women. The man inseminates the woman. Except here. This person would be born of a woman, but, since He was "her seed," he would NOT be the child of a man! Now think for a minute: if the Christ, who will bruise the enemy's head, is NOT the child of a man, but IS the child of a woman, how would that be known? The woman would have to be a virgin--if she was not, then her child could not be proved to be anyone other than a normally born human being.
So we see that here, right after imperfection, sin and death entered the creation, God's remedy was predicted: He would be human, but born of a virgin, and He would be the one to defeat the enemy.